Natural Patch Power: Moringa Pods and Katakataka Leaves vs. Staphylococcus aureus | InformativeBD

Cristine Joyce S. Buenaventura, Catherine B. Balaguer, Alexandrine Erica D. Barcelon, Ayessa Mae D. Cortes, Denise Mikaela A. Doroja, and Darylle Cesar G. Hilapo, from the different institute of Philippines. wrote a Reseach Article about, Natural Patch Power: Moringa Pods and Katakataka Leaves vs. Staphylococcus aureus. Entitled, Moringa pods (Moringa oleifera) and katakataka leaves (Kalanchoe pinnata) extract as a natural-derived medical patch against Staphylococcus aureus. This research paper published by the International journal of Microbiology and Mycology (IJMM). an open access scholarly research journal on Microbiology . under the affiliation of the International Network For Natural Sciences| INNSpub. an open access multidisciplinary research journal publisher.

Abstract

This study investigated the effects of Moringa pods (Moringa oleifera) and Katakataka leaves (Kalanchoe pinnata) extracts on Staphylococcus aureus (S. aureus), a bacterium often causing skin infections. The researchers prepared ten treatments using a 95% ethyl alcohol solution and dried plants, which were then tested for their inhibitory effects on S. aureus growth. The results showed that treatments with Moringa pods extract, both alone and combined with a medical patch, significantly inhibited S. aureus growth, with zones of inhibition measuring 2.4cm and 2.7cm respectively. Conversely, Katakataka leaves extract showed little to no inhibition and even seemed to facilitate S. aureus growth. Statistical analysis using One-way ANOVA and Tukey’s HSD test revealed significant differences between treatments, with those containing a higher percentage of Moringa pods extract proving more effective. This suggests that Moringa pods extract could be a potent natural-derived medical patch against S. aureus.

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Introduction

In order to keep the skin's physiological functions working, wound healing is a necessary procedure. Thus, if bacteria enter a wound and begin to multiply, an infection may develop, impeding the healing process of the wound (Leonard, 2023). The best technique for wound healing and infection control is dressing application. This lessens discomfort and improves the hypoxic environment's ability to promote healing (Nguyen et al., 2023). It also helps to maintain the environment's moisture content and temperature. Herbs have been utilized by humans for wound care since the dawn of time. According to a 2019 study by Doña et al., alternative medicine is becoming more popular due to the high cost of synthetic drugs and the possibility of genetic resistance developing in some microorganisms. Because of its uses in conventional medicine, the medicinal plant Kalanchoe pinnata is known to demonstrate antibacterial efficacy against a variety of diseases and their mechanisms of action, according to Tajudin et al. (2022).

The amazing tree of Moringa oleifera is rich in bioactive substances and a good source of pharmaceutical compounds including flavonoids, phenolic acid, and polyphenols, it is thought to have medical benefits like antioxidant, tissue protection, antiinflammatory, and analgesic (Chis et al., 2024). Natural polymers represent a potential class of materials for the development of skin wound dressings that can hasten the healing process and boost defense against infections (Ansari and Darvishi, 2024). Moreover, skin has extraordinary regenerating capabilities. When this regeneration process is occasionally disrupted and wounds heal slowly, patients face serious health risks because the available patches, dressings, and gauzes are insufficient to initiate a physiological wound healing process, which can lead to the formation of new lesions.

The purpose of this study is to investigate the possible application of Katakataka leaves (Kalanchoe pinnata) and Moringa pods (Moringa oleifera) extract as a naturally derived antibacterial medical patch.

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