Mahmood Khan Yousufi from
the institute of India and Narendra
Kumar Thapak, from the institute of India.
wrote a Research article about, Biopiracy at Sea: The Emerging Threat to
Marine Biodiversity. Entitled, Biopiracy of marine organisms: an emerging
paradigm. This research paper published by the Journal of Biodiversity and Environmental Sciences | JBES. an open access scholarly research journal
on Biodiversity. under the affiliation of the International Network
For Natural Sciences| INNSpub. an open access multidisciplinary research
journal publisher.
Abstract
The modern drugs commercially available nowadays are widely isolated from natural reservoirs. Penicillin was isolated from a mold and Aspirin was isolated from a willow tree. The recent advanced scientific research has further extended the explorations for medicinal drugs in the marine reservoirs. Some of the drugs based on marine organisms have proved to be quite effective in treating diseases like cancer and Human Immunodeficiency Virus. The different marine organisms like sponges, molluscs, echinoderms, tunicates and bryozoans are being actively used or trialled for the preparation of useful pharmaceutical drugs. The scientists, researchers and pharmaceutical corporations of the world compete to discover new drugs from global marine reservoirs. The marine organisms are freely available in the marine ecosystems and lack of global legislations provide free hands to the biopirates to exploit the marine reservoirs and isolate different organisms from it. The enormous explorations in the marine reservoirs by the biopirates are causing damage to its ecosystems and its lifeforms. In this investigation, it was concluded that though scientific explorations should be allowed in the marine reservoirs for producing lifesaving drugs but overexploitation of marine reservoirs should be prohibited. It is suggested through this investigation that proper tracking of marine reservoirs is the present requirement to face the challenges being laid down by the biopirates.
Read more : Solvent Matters: Phenolics and Flavonoids in Freshwater Clam Extracts | InformativeBD
Introduction
The marine water
accounts for about 97% of total water present on the land area of this blue
planet (Munn, 2003). The marine ecosystems comprise of rich biological
diversity that includes, plants, animals, and various microscopic life forms.
The scientific explorations around the globe are incorporating global marine
ecological resources. The fact sheet of United Nations interprets in the ocean
conference held in the year 2017 that the global oceans comprises of 500000 and
10 million marine species (United Nations, 2017). The marine phytoplanktons
produces 50 percent of oxygen on earth (Bittel, 2019). The species heterogeneity
associated with the marine ecosystems lies between 0.7 to 1.0 million species
with millions of bacteria, viruses and other microbial species (United Nations,
2017). The results of various research investigations depict that global marine
resources have been often utilized by local individuals residing near the
marine reservoirs as nutritional source and for curing health ailments. At
present, about 7.5% of the global marine reservoirs are safeguarded (Briggs,
2020). World Wildlife Federation suggests a term ‘Marine Protected Areas’ that
involves efficiently managing or safeguarding the marine ecological reserves
and the habitats of various life forms associated with it (Reuchlin-Hugenholtz
and McKenzie, 2015). According to the International Union for Conservation of
Natural Resources during world conservation congress, various global states
agreed Motion 53 that mainly urged to safeguard 30% of the global marine
ecosystems up to 2030 (Dinmore, 2016).
Various historical
evidences depict that variety of marine life forms were employed for medicinal
usage. The written record of medicinal herbs dates back to about 5000 years
(Pan et al., 2014). In China in 2953 BCE in the empire of Fu Hsi taxes were
levied on the medicines derived from fish (Newman, 2019). Hippocrates in 400
BCE observed antibiotic efficacy of some sponges and used it for curing wounds
of soldiers (Munn, 2003). The personal physician of the emperor Claudius
suggested the usage of electric fish viz. Torpedo nobilana secretions to treat
headaches and even migraines (Janik, 2014).
Romans used the algae
as medicines for the treatment of various health ailments (Anis et al., 2017).
Khalilieh and Boulos in their investigation described notable uses of micro and
macro algae extracts for curing health disorders (Khalilieh and Boulos, 2006).
Secundus in 1603exhibited the application of stingray spines to treat
toothaches (Narchi, 2015). The ancient Chinese medicinal literature available
in Chinese Materia Medica depicts that various marine organisms were utilized
in the ancient Chinese traditional medicinal therapies (Fu et al.,2016). The
use of marine invertebrates for healing purposes has also been reported during
ancient Greek times and the initial Byzantium (Voultsiadou, 2010). The use of
marine turtles for preparation of traditional medicines has also been reported
(Alves, 2006). The treatment of human health disorders from animals and their
isolated compounds is often called as zootherapy (Alves, 2006). In different
regions of Brazil, the fisherman uses different species of fish for medicinal
purposes (Pinto et al., 2015). A well-known medical Scholar Ibn Sina also
popularly known as Avicenna in his book “Canon of Medicine” depicts isolation
of medicinal material from skin of marine animals (Nizamoglu, 2015). There are
various marine organisms like sponges, corals, crabs, mollusks, and sea horses
that are used in various parts of Asia and other global regions in traditional
medicines (Kataona, 2015). Additionally, the sea life natural stores are also
the supplies of antimicrobial constituents like the cationic antimicrobial
peptides (Patrzykat, 2003).
From the above historical evidences, it is clear that the marine organisms have been employed for therapeutic purposes since ages. These evidences act as an attraction for the pharmaceutical corporations, researchers and scientists to deeply explore marine ecosystems for new biological innovations. With the passage of time and advancement in the technical research, the explorations in the ocean reservoirs have enormously risen. The insufficiency of global legislations to restrict uncontrolled explorations of global marine reserves is seriously causing damage to the global ocean life forms. The biopirates are exponentially isolating the marine organisms for manufacturing therapeutic drugs and subjecting them to patenting. The patent war between the pharmaceutical corporations to conquer monopoly over the marine ecosystems is definitely a matter of fact in the current scenario. Various pharmaceutical corporations are involved in manufacturing potential therapeutic compounds from marine lifeforms. Some of the significant pharmaceutical corporations are Santen Pharmaceutical Co. Ltd., Icos corporation, Island Kinetics Inc., HRD corporations, Procter & Gamble Company, Heliae Development LLC. and Codexis Inc. (Ninawe and Indulkar, 2014). The various patents being issued with respect to biologically active compounds isolated from marine organisms include US8486960 B2, US8450489 B2, US8445701 B2, US8586597 B2, USRE44599 E1, US8293943 B1, US8524980 B2, and US8586051 B2. (Ninawe and Indulkar, 2014). The pharmaceutical corporations are just performing theft of nature as biopirates and generating huge financial assets. The present study basically aims to explore this new challenge that is being created by the biopirates concerning biopiracy of global marine lifeforms.
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