Showing posts with label Diarrhea. Show all posts
Showing posts with label Diarrhea. Show all posts

Drinking Water Quality & Disease Risks in Rural Azad Kashmir | InformativeBD

Drinking water quality and risk of waterborne diseases in the rural mountainous area of Azad Kashmir Pakistan

Ali Akbar, Uzma Sitara, Shabir Ahmed Khan, Niaz Muhammad, Muhammad Iftikhar Khan, Yasir Hayat Khan, and Saeed Ur Rehman Kakar, from the institute of Pakistan. wrote a Research article about, Drinking Water Quality & Disease Risks in Rural Azad Kashmir. Entitled, Drinking water quality and risk of waterborne diseases in the rural mountainous area of Azad Kashmir Pakistan. This research paper published by the International Journal of Biosciences | IJB. an open access scholarly research journal Biosciences. under the affiliation of the International Network For Natural Sciences| INNSpub. an open access multidisciplinary research journal publisher.

Abstract

A study was conducted to evaluate drinking water safety at three different levels including sources, system and household in district Bagh, an earthquake affected area of Azad Jammu and Kashmir Pakistan. Portable water testing kit (Oxfam-DelAgua) was used for the detection of thermo-tolerant fecal coliform (Escherichia coli). A total (n=254) number of drinking water samples were examined for the presence of fecal coliform. It was found that, 68.5% (174 out of 254) of the overall samples tested were contaminated with Escherichia coli. The 52% (40 out of 77) of the water samples at source level, whereas 69% (58 out of 84) of water sample collected from system and 71% (66 out of 93) at household level were found contaminated with Escherichia coli. It was concluded that unprotected drinking water sources, improper management of waste, vulnerable sewage and ignorance regarding health and hygiene are the main reason of water contamination in the area.

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Introduction

Water is an important component of human body and is the need of life (Muhammad et al., 2012). Presence of deleterious chemicals and pathogenic microbes can cause a serious health problem, leading to infections and death (Lima et al., 2005). The drinking water contaminated with any pathogenic bacteria is unsafe for human consumption and household use (Muhammad et al., 2012). Access to safe drinking water is not only the prime need for survival and health but is also basic human rights (WHO, 2000). Safety of drinking water remains an important public health concern particularly in emergency situations (Ferretti et al., 2010). Pathogens that cause diarrheal diseases are being linked with contaminated water consumption, such pathogens are the main cause of gastrointestinal infections. The childhood mortality rate due to diarrheal diseases is 2.5 million each year (Muhammad et al., 2012; Oswald et al., 2007). Each year approximately five million children die due to the use of unsafe water (Shar et al., 2010). Approximately 1.8 million kids died in developing countries (excluding china) caused by biological agents or microorganisms originating from food and water in year 1998 (Akbar and Anal 2011). Vulnerable and Unsafe drinking water supplies are contributing in high rate of human morbidity and mortality worldwide. It has been a national concern in United States of America to provide safe drinking water since before the 20th century (Sobsey 2006). Unprotected or protected communal water sources are the key means of potable water in many developing countries (Gundry et al., 2004; WHO, 2000). It has been estimated that 1/3 of the total world population use ground water for drinking purpose (Nickson et al., 2005). Obtaining safe water from a communal source remains a prime concern of the people in developing countries (Joyce et al., 1996). Vulnerable sewage and sanitation lines and direct discharge of waste to natural reservoirs and water bodies are the major cause of fecal contamination (Huttly, 1990).

A group of bacteria called coliform are the primary indicator of water pollution. The presence of these microbes is associated with the presence of disease causing microorganisms (Muhammad et al., 2013; Shar et al., 2010). Bacteriological examination of water samples are usually undertaken to estimate the water quality. Most of the waterborne disease is related to faecal pollution of water sources. Therefore water microbiology is largely based on the need to identify indicators of faecal pollution such as Escherichia coli (Barrell et al., 2000). The detection and enumeration of coliform bacteria for the evaluation of microbiological drinking water quality has been exist from since 1912 (Bancroft et al., 1989). Drinking water should be pathogens free and with good organoleptic characteristics (Nevondo and Cloete, 1999). Contamination of drinking water during or after the collection from a safe source has been identified as a problem in rural areas particularly. A vast variety of pathogens are associated with water to cause severe diseases such as diarrhea, Poliomyelitis and hepatitis. The microbes such as, Vibrio cholera, Rotavirus, Astrovirus, Cryptosporidium, Gardia, Entameoba histolytica, Shagella etc are important pathogens, can cause severe damage to human health associated to unsafe water (Gundry et al., 2004; Hamer et al., 1998). In developing countries huge population are suffering from health problems associated with unavailability of drinking water or contaminated drinking water (Leeuwen, 2000).

In Pakistan it has been estimated that 40% of all deaths and 30% of all diseases is associated to unsafe water. Every fifth person suffers from illness due to polluted water. It has been estimated that three million Pakistanis suffer, while 0.1 million die from waterborne diseases annually (Haydar et al., 2009). It has been estimated that 44% of the Pakistani population does not have access to safe drinking water, while the figures rise to 80 percent in rural area population. Almost 1.1 billion people are lacking adequate access to water, whereas 2.4 billion people live without ample sanitation (Rosemann, 2005). The objective of this study was to evaluate and highlight the bacteriological quality of drinking water at three different levels such as, sources, water supply system and household and possible exposure to the pathogenic bacteria during daily consumption of water in the remote mountainous area of Azad Kashmir Pakistan.

Study area The study conducted in different areas of district Bagh, Azad Jammu and Kashmir Pakistan. Topography of the study area is mountainous and majority of the people used to live in small scattered villages dependent on natural springs particularly well and flowing water channels generally as their primary source of water (drinking and household use). The area was severely affected by October, 2005 earthquake (Figure1). In the current study a detail survey regarding the existing drinking water quality of the area in term of microbiological contamination was conducted.

Reference

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Barrell RAE, Hunter PR, Nichols G. 2000. Microbiological standards for water and their relationship to health risk. Communicable Diseases and Public health 3(1), 8-13.

Ferretti E, Bonadonna L, Lucentini L, Libera SD, Semproni M, Ottaviani M. 2010. A case study of sanitary survey on community drinking water supplies after a severe (post-Tsunami) flooding event. Annali dell’Istituto Superiore di Sanità 46(3), 236-241. http://dx.doi.org/10.4415/ANN_10_03_03

Gundry S, Wright J, Conroy R. 2004. A systematic review of the health outcomes related to household water quality in developing countries. Journal of Water and Health 2(1), 1-13.

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Haydar S, Arshad M, Aziz JA. 2009. Evaluation of drinking water quality in urban areas of Pakistan: A case study of southern Lahore. Pakistan Journal of Engineering and Applied Science 5, 16-23.

Huttly SR. 1990. The impact of inadequate sanitary condition on health in developing countries. World Health Statistics Quarterly 43, 118-126.

Joyce TM, Meguigan KG, Elmore-Meegan M, Conroy RM. 1996. Inactivation of fecal bacteria in drinking water by solar heating. Journal of Applied and Environmental Microbiology 62(2), 399-402.

Kress M, Gifford G. 1984. Fecal coliform release from cattle fecal deposits. Water Recourses Bulletin 20(1), 61-66. http://dx.doi.org/10.1111/j.17521688.1984.tb04642.x

Leeuwen FXR Van. 2000. Safe drinking water; the toxicologist’s approach. Food and Chemical Toxicology 38, 51-58. http://dx.doi.org/10.1016/S0278-6915(99)00140-4

Lieverloo JHM van, Blokker JME, Medema G. 2007. Quantitative microbial risk assessment of distributed drinking water using faecal indicator incidence and concentrations. Journal of Water Health 5(1), 131-149. http://dx.doi.org/10.2166/wh.2007.134

Lima JRO, Marques SG, Gonçalves AG, Filho NS, Nunes PC, Silva HS, Monteiro SG, Costa JML. 2005. Microbiological analyses of water from hemodialysis services in são luís, maranhão. Brazil. Brazilian Journal of Microbiology 36, 103-108. http://dx.doi.org/10.1590/S1517838220050002000 01

Muhammad F, Ikram M, Khan S, Khan K, Shah SH, Badshah Z, Ahmad W, Shah SN. 2013. Flood disaster in Charasadda, Pakistan: Bacteriological examination of drinking water. International Journal of Biosciences 3(5), 51-59. http://dx.doi.org/10.12692/ijb/3.5.51-59

Muhammad N, Bangush M, Khan AT. 2012. Microbial contamination in well water of temporary arranged camps: A health risk in northern Pakistan. Water Quality Exposure and Health 4(4), 209-215. http://dx.doi.org/10.1007/s12403-012-0080-0

Nevondo TS, Cloete TE. 1999. Bacterial and chemical quality of water supply in the Dertig village settlement. Water SA 25(2), 215-220.

Nickson RT, McArthur JM, Shrestha B, Kyaw-Myint TO, Lowry D. 2005. Arsenic and other drinking water quality issues, Muzaffargarh district, Pakistan. Applied Geochemistry 20, 55-68. http://dx.doi.org/10.1016/j.apgeochem.2004.06.004

Oswald WE, Lescano AG, Bern C, Maritza MC, Lilia C, Robert HG. 2007. Fecal contamination of drinking water within Peri-urban households, Lima, Peru. The American Journal of Tropical Medicine and Hygiene 77(4), 699-704.

Oxfam-DelAgua. 2004. Oxfam-DelAgua portable water testing kit, users manual (version 4.1), revised, Univ. of Surrey, Marlborough, U.K.

Rosemann N. 2005. Drinking water crisis in Pakistan and the issue of bottled water the case of Nestlé’s ‘Pure Life’. Swiss coalition of development organizations Swissaid, catholic lenten fund bread for all, Helvetas Caritas, Interchurch aid, 1-37.

Shar AH, Kazi YF, Kanhar NA, Soomro IH, Zia SM, Ghumro PB. 2010. Drinking water quality in Rohri City, Sindh, Pakistan. African Journal of Biotechnology 9(42), 7102-7107. http://dx.doi.org/10.5897/AJB10.410

Sobsey DM. 2006. Drinking water and health research: a look to the future in the United States and globally.  Journal  of  Water  Health  4(1),  17-21. http://dx.doi.org/10.2166/wh.2005.035

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Traditional Remedies for Diarrhea: Plant Inventory and Phytochemical Insights from Man, Côte d’Ivoire | InformativeBD

Plants used against diarrhea in traditional medicine of Man, western Côte d’Ivoire: Inventory and phytochemical screening

Ta Bi Irié Honoré, from the institute of Côte d’Ivoire. Aké-Assi Emma , from the institute of Côte d’Ivoire . and N’guessan Koffi, from the institute of Côte d’Ivoire. wrote a Research Article about, Traditional Remedies for Diarrhea: Plant Inventory and Phytochemical Insights from Man, Côte d’Ivoire. entitled, Plants used against diarrhea in traditional medicine of Man, western Côte d’Ivoire: Inventory and phytochemical screening. This research paper published by the Journal of Biodiversity and Environmental Sciences (JBES). an open access scholarly research journal on Biodiversity. under the affiliation of the International Network For Natural Sciences | INNSpub. an open access multidisciplinary research journal publisher.

Abstract

Diarrhea is a public health problem in Côte d’Ivoire. To contribute to the fight against the disease, this study was undertaken in the city of Man from January 2 to May 31, 2024 with traditional practitioners in the city. It allowed us to interview 88 people practicing in this field of traditional medicine. The study inventoried 30 plants belonging to 17 botanical families with a dominance of Fabaceae and Euphorbiaceae. The leaves, leafy stems, roots and whole plants are the parts of the plants used in anti-diarrheal treatments. These plant organs are prepared by decoction, maceration, kneading and trituration. The medicinal recipes are administered as decoction orally and as purge anally. The plant species cited during this study are: Amphicarpaea bracteata (FCe = 0.58) and Ocimum gratissimum (FCe = 0.49). A phytochemical screening was carried out on the aqueous extracts of these two plants to search the scientific basis of their anti-diarrheal properties. These tri-phytochemical tests indicated the presence of sterols, polyterpenes, polyphenols, flavonoids, alkaloids and saponins. These chemical groups could justify the use of these plants in traditional medicine. These two plant species should therefore be the subject of more in-depth pharmacological tests for the implementation of new molecules against diarrhea.

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Introduction

Current knowledge places the beginning of humanity at 7 million years ago (Guy, 2009). Since then, man has used plants (Ta et al., 2023). This observation is linked to the use of plants in various areas of life, such as housing, food and health (N'guessan, 2008). The relationships between man and plants have led to the emergence of several sciences: ethnobotany, ethnomedicine, ethnopharmacology. Ethnopharmacology is the interdisciplinary scientific study of all materials of plant, animal or mineral origin and the knowledge or practices related to them, which vernacular cultures implement to modify the states of living organisms for therapeutic, curative, preventive or diagnostic purposes (Fleurentin, 2012). It is also called traditional medicine which is based on empirical knowledges and pratices. Today, the use of plants for health is widespread not only in developing countries but also in developed societies (Doh et al., 2023). Like other countries, the traditional medicine of Côte d’Ivoire, offers remedies for all human pathologies even if they are curable for modern medicine. The conditions treated are diverse: asthma, diabetes, high blood pressure and especially diarrhea, the subject of this study. Diarrhea is a transit disorder characterized by soft or liquid stools, in abnormally high quantities or with an increased frequency of occurrence (Randremanana, 2012). It can be caused by bacterial, viral or parasitic infections. Diarrhea is the third leading cause of death at any age (Assogba, 2012) and the 5th leading cause of premature death in the world (WHO, 2014). In Côte d'Ivoire, diarrhea is a public health problem. However, the management of diarrheal diseases is limited by the inaccessibility of certain populations to hospitals and the high cost of pharmaceutical drugs (Ambé et al., 2015). In Man, the site of this study, diarrheal diseases are the 2nd cause of consultation after malaria. Faced to this worrying health situation, the use of plants becomes an appropriate solution. This study is part of this perspective. It is therefore a contribution to the search for new plants of anti-diarrheal properties. It lists the plants proposed by traditional practitioners of Man against diarrhea and seeks the scientific basis for their use through a phytochemical screening.

Reference

Aké CB, Ta BIH, Koné MW. 2019. Some minerals of nutritional and therapeutical importance from the leaves and stems of Piper guineense Schum. & Thonn. (Piperaceae) GSC Biological and Pharmaceutical Science 8, 104–108.

Aké-Assi E, N’guessan K, Kouassi AF. 2015. Evaluation of the acute toxicity of the aqueous extract of the leaves of Thunbergia atacorensis, a new species. European Scientific Journal 11(27), 92-100.

Aké-Assi L. 2011. Compendium of African medicine and pharmacopoeia: some plants traditionally used in primary health care coverage. NEI-CEDA Edition, Abidjan (Côte-d’Ivoire), 157p.

Ambé ASA, Ouattara D, Tiebre MS, Vroh BTA, Zirihi GN, N’Guessan KE. 2015. Diversity of medicinal plants used in the traditional treatment of diarrhea in the markets of Abidjan (Côte d’Ivoire). Journal of Animal & Plant Sciences 26, 4081-4096.

Assogba AL, Ehui E, Maïga MF, N’Guetta NEE, Randremanana RV, Sehonou J, Seukap E. 2012. Initiation against diarrheal and enteric diseases in Africa: a contribution to the fight against cholera. Medicine of Black Africa. 7p.

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Doh KS, Ta BIH, Yapo YCV, N’guessan K. 2023. Phytochemical screening and acute toxicity assessment of leaves from Piliostigma thonningii (Fabaceae), a plant used in traditional medicine against diabetes in Côte d’Ivoire. Journal of Pharmacognosy and Phytochemistry 12, 19-23.

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Ta BIH, Doh KS, Yéo S, Aké-Assi E, N’guessan K. 2023. Study of the acute toxicity of aqueous extracts of Alchornea cordifolia (Euphorbiaceae) and Tithonia diversifolia (Asteraceae), two plants frequently cited in traditional medicine in Ivory Coast. Ivorian Review of Sciences and Technologies 42, 349-362.

Ta BIH, N’Guessan K. 2021. Ethnopharmacological study of hypotensive plants found in the markets of Abidjan, Ivory Coast. International Journal of Innovation and Applied Studies 32, 522-530.

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