Jayaprakash Kuzhandaivel , Balamurugan Vadivel and Rajasekar Aruliah from the different institute of the india, wrote a research article about Green Synthesis: Silver Nanoparticles from Moringa oleifera, entitled, Antimicrobial and antioxidant properties of silver nanoparticles from Moringa oleifera gum: a green synthesis approach. This research paper published by the International Journal of Biosciences| IJB an open access scholarly research journal on Bioscience, under the affiliation of the International Network For Natural Sciences | INNSpub, an open access multidisciplinary research journal publisher.
Abstract
Plant gums have enormous medicinal potential and have been used in the pharmaceutical and biomedical fields. In the present investigation, Moringa oleifera gum (MOG) was collected, and its physical properties and phytochemical composition were investigated. Silver nanoparticles (AgNPs) were produced, and characterization was carried out using UV spectroscopic analysis and scanning electron microscopy (SEM). In this study, the standard method was used for the antioxidant assay and the antimicrobial test. The synthesized nanoparticles (NPs) have irregular shapes and no fixed geometry. The agglomerate shape resembles that of pebble-like structures. UV‒vis analysis proved the wavelength of the sample to be 350–470 nm. In antioxidant studies, the synthesized AgNPs exhibited significant DPPH radical scavenging activity values ranging from 21.15 ± 0.017 to 63.46± 0.03 g/mL at concentrations ranging from 100 to 500 g/mL. In an antimicrobial experiment, the maximum incubation zone was 18 mm by 100 µL of AgNPs synthesized from M. oleifera gum extract against S. typhi. P. aeruginosa expressed a 16 mm zone of incubation at 100 µL of AgNPs synthesized from M. oleifera gum. According to the findings of this study, AgNPs derived from M. oleifera gum can be employed as a lead chemical in the creation of an effective antimicrobial drug for the treatment of microbial infections. This research establishes the foundation for synthesizing AgNPs from M. oleifera gum and its powerful novel pharmacological applications.
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Introduction
Plant gums have tremendous therapeutic importance in pharmaceutical preparations such as tablets, lotions, suspensions, syrups, and ointments. Plant gums are made of polysaccharides that can be used in various formulations and chemical changes to improve their properties [H Zaigham et al., 2019;].Researchers are actively attempting to develop a wide range of novel synthetic and semisynthetic compounds from natural resources that are incredibly beneficial to humans and animals.
The bioactive compounds derived from plant gum can be extracted using current technological advances. Moringa oleifera is a widely distributed plant species used for medicinal purposes. oleifera comes under the Moringaceae family and is fast-growing, droughttolerant, and readily adapted to various habitats and agricultural systems. The plant is native to northeastern India and is commonly found in tropical and subtropical regions [SJS Flora and V Pachauri,2011;]. In the Indian vegetable industry, it holds adistinct and coherent stance. M. oleifera has been used as a food additive because of its high nutritional content and easy digestion of proteins, minerals, vitamins, and carotenoids [JW Fahey,2005; K Maheshwari et al., 2014; J Mehta et al.,2011].
Pharmaceuticals based on metals, polymers, liposomes, and oxide
nanoparticles are being researched for their therapeutic potential in
many diseases, including cancer [O C Farokhzad et al.,2006;]. Metal nanoparticle
synthesis has emerged a san essential branch of nanotechnology, with a growing
commercial demand for NPs due to their numerous applications. Researchers have
been interested in AgNPs because of their unique properties. In this research,
AgNPs have been characterized as antibacterial agents. Silver 'santibacterial
action is magnified in the form of NPsdue to the increased number of NPs per
unit area(increase in area/surface/volume ratio) [M Araujo etal., 2020;]. In
the present investigation, Moringaoleifera gum (MOG) was collected, and its
physical properties and phytochemical composition were analyzed. The green
production and characterization of AgNPs from M. oleifera gum were then carried
out utilizing UV-spectroscopic analysis and SEM. Several studies have reported
that M. oleifera plant parts suchas leaves, stems, and seeds have shown suitable antibacterial
activities [S Gupta et al., 2018;].However, because there has been no
previous research on M. oleifera gum, the current work focuses on the
antimicrobial characteristics of AgNPs generated from M. oleifera gum.
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